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Exacerbations of COPD

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Other pathways, such as AMP-activated protein kinase (AMPK), phosphoinositide 3-kinase/protein kinase B (AKT), cAMP/protein kinase A (PKA)/cAMP response element-binding protein (CREB), and signal transducer and activator of transcription 3 (STAT3)/Snail, are involved in other crucial FNDC5/irisin functions (Wang et al., 2022

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