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However, the dual activity of KYNA, antagonizing NMDARs and 7nAChRs both of which are critical for normal brain function complicates pharmacological targeting, as achieving therapeutic modulation within an optimal window risks unintended and potentially severe side effects

As a primary apoptosis inhibitor, XIAP can bind to caspase-9 and caspase-3 to block active caspase and inhibit apoptosis

Making better chimeric antigen receptors for adoptive T-cell therapy

Quantification and (13)C-Tracer analysis of total reduced glutathione by HPLC-QTOFMS/MS

There was a significant drop during the first six months of 2025/26 with uptake at 63.5%