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Kinase Akt mediates NQO1 phosphorylation at T128 residue, which induces ubiquitination and degradation and ultimately, inhibition of the antioxidative properties of NQO1 [47]

To sustain and for precision-targeted delivery of melatonin intravenously, a nano-PM compound, namely, PM/MS@Melatonin, i.e., nanospheres coated with a platelet membrane (PM) loaded with melatonin, is designed (Zhang et al., 2021)

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CG'806, a First-in-Class FLT3/BTK Inhibitor, Exerts Superior Potency Against AML Cells Harboring ITD, TKD and Gatekeeper Mutated FLT3 or Wild-Type FLT3

& Giguere, V