4-hne glutathion peroxidase Role of lipid peroxidation derived 4-hydroxynonenal (4-HNE) in cancer: Focusing on mitochondria Simplified scheme showing ROS and

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on the other hand, it promotes transcriptional expression of GPX4, protecting cells from OS and inhibiting ferroptosis ( Obviously, ferroptosis is a process regulated by multiple factors (Table 1) and involves many clinical applications

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