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ALK is a therapeutic target for lethal sepsis

[PMC free article: PMC4526153] [PubMed: 24220094] 544

For example, iron overload promotes the inflammatory response in macrophages by increasing the ability of 5-LOX to bind to the nuclear membrane

Blood was collected into 2 ml K2EDTA Vacutainers, mixed carefully by up-and-down rotation, aliquoted into 6 microtubes of 150 L/each and frozen at 80 C