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Together, these data reinforce the model that KG and carnitine are upstream of histone acetylation to drive resistance to DNA-damaging agents directly

Based on the positive results of this study, a next-generation DNA vaccine has been developed using residual patient tumor and blood samples from patients vaccinated in the phase III clinical study

This is particularly crucial for skeletal muscle and cardiac tissue, which are highly dependent on fatty acid oxidation

Compared with mammals, fish have lower abilities to use carbohydrates as energy sources, thus fish cannot use glucose to produce energy efficiently 10

These histopathological results confirm that the reduced swimming speed and weaker muscle endurance observed in the LMNA mutant transgenic fish are indeed associated with the presence of abnormal muscle development