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Contraindications and precautions: Use caution in patients with a history of asthma, sulfite sensitivity, or known allergy to glutathione or any formulation components

Exclusion criteria included malignancy, cirrhosis, hepatic insufficiency, renal failure, pregnancy, or viral coinfections

To achieve reasonable runtimes (on the order of a few minutes for a run of several thousand iterations), the size of the search space is further constrained by placing an upper limit on the number of reactions that can be used to construct a pathway

Cells under chronic ferroptotic stress exhibited increased sensitivity not only to the ferroptosis inducer RSL-3 but also to hydrogen peroxide

Preclinical and Clinical Studies with Antioxidants Although evidence of oxidative damage in ALS pathogenesis has been largely described in the literature, all antioxidants tested in patients have so far failed, remaining unclear whether any antioxidant therapies might be effective for treating ALS