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i) Primary Pharmacological Actions of 5-Amino-1MQ: No It is not a neurotransmitter agonist 5-Amino-1MQ does not bind to or activate any known: Dopamine receptors Serotonin (5-HT) receptors GABAA or GABAB Cholinergic or adrenergic receptors Primary Mechanism of Action Inhibition of NNMT (Nicotinamide N-Methyltransferase) Main action : Inhibits NNMT, an enzyme that methylates nicotinamide (vitamin B3 derivative)

Concentration Math Insulin Syringe Units (U-100, 100 units = 1 mL) Yield at maintenance: at a 1.2 mg combined dose per week, the vial provides ~3 weeks of dosing (15 mg 1.2 mg/wk = 12.5 weeks at total mass, but draws of 16 units twice a week or 16 units once a week land at ~3 weeks of practical use given common dosing patterns)

When nerves are compressed, they cannot transmit signals related to movement and sensation to the brain

This process is not about expanding access broadly, but defining what fits within a tightly regulated, patient-specific compounding role