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Description

Our results suggest that CBS of the TSS pathway plays an important role in maintaining cysteine levels under restricted cystine availability or excess hemin exposure, and CBS upregulation by DMF increases the cellular glutathione levels to protect against ROS and ferroptosis stress in SCD

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doi: 10.1177/1933719115592713 157 GuptaSGoldbergJMAzizNGoldbergEKrajcirNAgarwalA

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