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Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy

These findings demonstrate that MYC acts as a transcriptional repressor, directly binding to the MAS1 promoter and negatively regulating its expression

Evidence shows that during ferroptosis, tumor cells supply arachidonic acid for eicosanoid synthesis, which can strengthen antitumor immunity (Yang et al., 2014)