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As previously reported, Hmox-1 expression could result from NO release in response to shear stress

Ascorbate is regenerated from the Asc by the action of (i) NADH- and NADPH-dependent dehydroascorbate reductase [128130], (ii) GSH-dependent dehydroascorbate reductase [131] or (iii) pH-dependent disproportionation reaction, which results in the formation of ascorbate and dehydroascorbate [132,133]

10.1016/j.devcel.2021.02.009 115 NiI.JiC.VijN

Yildirim, R

Therefore, understanding the molecular events underlying the benefit of fasting and through which cancer cells manipulate the challenges of both oncogenic signal and energetic stress merits in-depth investigation