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Since the aforementioned proteins were captured with Pf Prx1m in triplicate in our study and have already been reported to be redox regulated in other organisms, Pf Prx1m might play a role in regulating this important step of energy metabolism in Plasmodium falciparum

[DOI] [PMC free article] [PubMed] [Google Scholar] 599.Yoon HS, et al

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The study found that clinical activity index scores, depression scores, calprotectin (a marker of inflammation in the gut), and CRP levels all improved with high-dose treatment

Among the overlapping downregulated genes were Pparg and Cebpa , master regulators of fat cell metabolism, insulin sensitivity and adipogenesis, and Ppargc1b , a transcriptional coactivator for PPARs 31