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To reduce clearance and increase the serum half-life, polyethylene glycol-5000 (PEG5000) was conjugated to the molecule

This design additionally enables prolonged circulation time and controlled release of the therapeutic agent, ultimately achieving precise delivery to tau-related Alzheimer's pathological lesions in AD mice (Zhou et al., 2020)

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The overall mortality rate among adults with SE is approximately 20%, and patients who have a first episode of SE are at substantial risk for future episodes and the development of chronic epilepsy (Xu et al

Despite their promising benefits, its essential to consider potential peptide side effects, as they vary based on individual response and usage