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Evidence for hyperplasia (formation of new muscle fibers) needs even longer finding periods and specialized assessment techniques

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However, the pathogenesis of AD is much more complex and oxidative stress may play a patho-physiological role (Sultana and Butterfield 2010)

In observational studies, CKD and dialysis patients who received calcitriol or synthetic vitamin D analogs (active forms of vitamin D that do not require the kidney for activation) exhibited reduced cardiovascular and all-cause mortality (Zheng 2013)

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