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Intracellular NAD + levels are reduced by nuclear receptor liver X receptor-alpha (LXR) agonists in a CD38-dependent manner, thereby reducing the infection of macrophages

Sachse C, Smith G, Wilkie MJ, Barrett JH, Waxman R, Sullivan F, Forman D, Bishop DT, Wolf CR Colorectal Cancer Study G (2002) A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer

The PATTERN study first confirmed the benefit of carboplatin combined with paclitaxel over the cyclophosphamide, epirubicin, fluorouracil, and docetaxel regimen in the adjuvant settings in TNBC patients

These findings indicate a positive effect of N nutrition on the expression of PR proteins which could be linked to disease resistance

doi: 10.1371/journal.pone.0083466 13 FoyerC