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Unfortunately, the absence of population-level screening and the protean nature of early symptoms mean that fewer than one quarter of patients are diagnosed at a surgically curable stage

4-Methylumbelliferone also prevents the expression of CSC markers during hepatocarcinogenesis [53]

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset

Rat model studies demonstrate rise of about 15% in zinc within 24 h post-injury at the wound margins, followed by an increase of up to 30% during the formation of granulation tissue and epidermal proliferation [532, 533]

By attaching specific ligands to the surface of polymer NPs, drug accumulation at the disease site can be increased, concentration at the target area improved, and systemic distribution reduced