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The authors demonstrated, coptisine exhibits an inhibitory effect on macrophage polarization by regulating m6A methylation of tuberous sclerosis complex

Kranz, R

Pharmacological inhibition of vanin-1 using RR6 also did not significantly affect insulin sensitivity or fasting blood glucose levels 42,43

This emphasizes the importance of individualized care plans for elderly diabetes patients, balancing glycemic targets with the risk of hypoglycemia and other adverse effects