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Melatonin's role in the stimulation of antioxidant enzymes was first identified where it was found to markedly increase the activity of glutathione peroxidase (GPx)

The diverse roles of melatonin in fertility regulation underscore the importance of further exploration (20), and the complex interplay between melatonin biosynthesis and regulation in reproduction has sparked widespread interest in its potential role in assisted reproductive technology (ART) (21)

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