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[DOI] [PubMed] [Google Scholar] 87.Collins P.B., Chaykin S

Features that blunt immune competence include dominant tumor-associated macrophage programs, sparse and dysfunctional effector T cells, endothelial remodeling that restricts lymphocyte entry, and neuronimmune circuits that reinforce suppression

The role of NIK in mediating IL-23 production in DCs has also been linked to other mouse inflammatory diseases, including the skin inflammatory disorder psoriasis and autoimmune inflammation [50, 77]

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Add to this the fact that some individuals are more prone to vitamin B12 deficiency, and the confusion is compounded