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Hydroxocobalamin, the form most used in the UK, is released gradually, and a maintenance dose is often given every eight to twelve weeks

doi: 10.1016/j.ecoenv.2021.112083 16 DasA.MukherjiS

Annu Rev Immunol (2019) 37:45795

Multiple studies, extensively reviewed elsewhere, examining older adults (largely centenarians) found that those with longer lifespans had either higher serum levels of selenium or much lower percentages of selenium deficiencies, suggesting that inadequate selenium could adversely affect optimal health in aging populations (Giovannini et al., 2018)

You'll feel a quick pinch when the needle goes in, but after that, most people don't feel anything