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(2020) 4(6):e1900286

Hyperferritinemia is a feature identified in IIM-related interstitial lung disease that has been linked to disease severity and prognosis (153156)

Pathophysiology (The Mechanism of Disease) The brain relies heavily on folate for three critical processes: Methylation Reactions: 5-MTHF is a key methyl donor for the conversion of homocysteine to methionine, which is then converted to S-adenosylmethionine (SAMe)