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This remodeling is consistent with a shift in the fissionfusion balance toward excessive fission and/or compromised fusion dynamics under cisplatin-induced stress

As part of Crohn's disease, inflammation can occur in any section of the gastrointestinal tract, whereas ulcerative colitis is typically confined to the colon (42)

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An additional aspect that needs to be taken into consideration, specifically when performing surgical resection, is the loss of function within the organ