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Diet-induced obese animals exhibit indices of altered central monoaminergic neurotransmission, including reduced hypothalamic 1 adrenoceptor binding, enhanced electrophysiological responsiveness to norepinephrine application, decreased basal hypothalamic serotonin and dopamine levels, and reduced mesolimbic dopamine activity

References For Further Reading (1) F Gorouhi and H I Maibach (2009) Role of topical peptides in preventing or treating aged skin -International Journal of Cosmetic Science, 2009 Oct, Volume 31 (Issue 5), Pages 327-45

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