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The global conformational changes that permit this transport activity seem conserved among ABC transporters 3

They are somewhere in the middle of amino acids and full proteins

Iron sensing and signalling

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134 have generated an anti-idiotypic antibody (CG-86) which mimics an epitope on porcine GH and investigated the inhibitory effects on GH signaling and cell proliferation, which demonstrated the potential utility of this approach for generating GH antagonists