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Supplementary material The Supplementary Material for this article can be found online at: Abbreviations AEs, Adverse events

Furthermore, the salivary secretions, gastrointestinal mucosal secretions and factors of intra-luminal microflora jointly preserve the normal homeostasis (28, 29)

The cellular uptake of nanoparticles involves various endocytic pathways, including phagocytosis, macropinocytosis, clathrin- and caveolin-mediated endocytosis

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