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Some individuals might experience mild discomfort at the injection site, a bit of nausea, or occasional headaches

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however, their immunosuppressive properties make their systemic use problematic and favour the use of calcineurin inhibitors in topical or device coating applications ( Figure 1 )

Mitochondria are central to the health of cells and tissues and act as decisional hubs for cellular responses by integrating different physiological and pathological input signals