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Occurrence, abundance and elimination of class 1 integrons in one municipal sewage treatment plant

Lang, F., Artunc, F

We found higher levels of LAMP1 in APOE 3/4 + PSEN1 fibroblasts (Figures 6A, B) which aligns with previous studies displaying elevated LAMP1 levels and its mRNA in AD patients cortexes ( PSEN1 mutations generate a defect in the N-glycosylation of the V0a1 subunit of the v-ATPase, causing problems in its transport toward the lysosomes

This does not automatically mean that the person has a genetic mitochondrial disorder

Reduce mercury exposure from diet and environment and consider appropriate testing if exposure is a concern