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Telomerase is the ribonucleoprotein enzyme responsible for maintaining telomere length at the ends of chromosomes, and its progressive decline is a hallmark of cellular senescence

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For topical administration routes, including dermal and ocular delivery, hydrogels and nanogels are often limited by suboptimal skin permeability, poor adhesiveness, and challenges in large-scale manufacturing (Grillo et al., 2019

Saddle nose deformity may be a symptom of more serious autoimmune disorders including relapsing polychondritis and granulomatosis with polyangiitis, making timely medical assessment even more critical