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Why Smoking Increases the Risk of Cancer Smoking is one of the leading causes of cancer worldwide

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Mutations in the GTPases optic atrophy 1 (OPA1) and Mfn2 are associated with autosomal dominant optic atrophy and Charcot-Marie-Tooth neuropathy type 2A, and suggest a role for abnormal mitochondrial fusion in the pathogenesis of these human diseases (Zerihun et al., 2023)

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