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Cholesterol overuptake inhibited the secretion of GZMB and IFN- by CD8 + T and CD4 + T cells, promoting PD-1 expression in these T cells [125, 126]

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doi: 10.1016/j.psj.2024.103490 25 LiuH.WangX.DingC.HanX.ChengA.WangS.et al

Studies of Chinese Han population indicated that the T allele shown associated with schizophrenia as a risk allele 52 while a casecontrol association between the MTHFR C677T polymorphism and schizophrenia in a Japanese subjects research also demonstrated a strong linkage between the MTHFR C677T polymorphism and schizophrenia 53

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