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One is an NAD + -dependent glutamate dehydrogenase ( GDH2 ) and the other is an NADPH-dependent glutamate dehydrogenase ( GDH3 )

[DOI] [PubMed] [PMC] Korshavn KJ, Satriano C, Lin Y, Zhang R, Dulchavsky M, Bhunia A, et al

However, the question of causality versus association still remains, and the direct/indirect mechanisms by which the acrolein adducts may lead to injury remain to be determined

Studies have connected genetic variations in OATP1A1 to malfunction

Parallel work highlights possible impacts on keratinocytes and skin topography, where improvements in parameters such as fine lines and density were suggested