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IGF-1 exerts protective effects over mitochondria by preserving it from the oxidative damage generated by augmented metabolism, and increasing ATP synthesis and reducing intramitochondrial production of free radicals [105107]

CrossRef The Prognostic Significance of the Metabolic Score for Insulin Resistance and Subclinical Myocardial Injury for Cardiovascular Mortality in the General Population Patrick Cheon, Shannon OConnor, Saeid Mirzai, Mohamed A

Abbreviations MNTI: Melanotic Neuroectodermal Tumor of Infancy CT: Computed Tomography HMB: 45-Monoclonal Antibody to Melanosome AE1/AE3: Cytokeratin AE1/AE3 EMA: Epithelial Membrane Antigen NSE: Neuron-Specific Enolase GFAP: Glial Fibrillary Acidic Protein S: 100-S-100 Protein BRAF: V600E-Specific Mutation in BRAF Gene References Almomani MH, Rentea RM