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10.1111/jnc.12094 14 ChenX.JheeK.-H.KrugerW

In the present study, we mapped S- glutathionylation of recombinant, human parkin proteins to cysteines 59, 95 and 377

In vitro , adequate Se concentrations decreased apoptosis and oxidative stress markers and increased proliferation and testosterone production of sheep Leydig cells by affecting p-ERK1/2 signaling, steroidogenic enzyme activities, and miR-200a/NRF antioxidant pathway (168)

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Adverse health effects have been observed at both extremes of intake, with a narrow optimum range