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A fascination with enzymes: the journey not the arrival matters

Abstract The vagus nerve has an important role in regulation of metabolic homeostasis, and efferent vagus nerve-mediated cholinergic signalling controls immune function and proinflammatory responses via the inflammatory reflex

SuperPred is a web-based tool designed to predict the Anatomical Therapeutic Chemical (ATC) classification and potential targets of compounds, whereas STP uses multi-logistic regression models, leveraging 2D and 3D fingerprint similarity to forecast the likely targets of compounds

Indeed, by deconvolution of the total acyl-CoA dehydrogenase activities for the various chain lengths, we could fit the specificity for the chain length as well as the V max values of SCAD, LCAD and VLCAD to a single parameter set for MCAD-KO and wild-type mice (Additional file 3: Text S3)