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doi:10.1155/2012/324832 Pickart L, Margolina A

doi: 10.1056/NEJM197706232962502 25 SonKBLeeTJHwangSS

Upon CCCP treatment, Miro interacting with wild-type LRRK2 was degraded with time, while in the LRRK2 G2019S mutant, Miro showed decreased interaction with the mutant as well as resistance to degradation, delaying mitochondrial arrest and clearance in iPSC-derived neurons (Singh et al., 2019)

Conjugation can be either enzymic or non-enzymatic, nevertheless, GSH transferases are widespread in both animals and plants, and enzymatic conjugation is assumed to be particularly effective and may even result in GSH depletion

Moreover, short- and long-term tunicamycin treatments that trigger ER stress via UDP-HexNAc inhibition were ineffective against ferroptosis (Supplementary Fig