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In cases like these, you just cant rely on once-a-week or once-a-month shots, which are unfortunately the doses doctors most often prescribe

10.1016/j.pep.2011.07.003

Opened: A Critical Distinction This is where a lot of the confusion comes from

In comparison to traditional PSs, activatable PSs (aPSs) can be considered as PDT prodrugs, which remain inactive and non-toxic in their OFF state but transition to an ON state in response to specific stimuli present in the tumor microenvironment 30,31,32,33,34