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J Pharmacol Exp Ther 256:11891194 Shigesawa T, Sato C, Marumo F (1992) Significance of plasma glutathione determination in patients with alcoholic and non-alcoholic liver disease

For example, though vitamin C is unlikely to cause toxicity in healthy people, it can lead to tissue damage and fatal heart abnormalities in those with hemochromatosis, an iron storage disorder ( Side effects related to overconsuming fat-soluble vitamins Because fat-soluble vitamins can accumulate in your bodys tissues, they can cause much more harm when taken at high doses, especially over long periods

Oxidative stress in small vessel disease

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Int J Dev Neurosci 10:143152 Nehlig A, de Vasconcelos AP (1993) Glucose and ketone body utilization by the brain of neonatal rats