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Despite these advances, significant translational challenges remain, including nanotoxicity, long-term safety, large-scale GMP manufacturing, regulatory barriers, and cost-effectiveness

The long non-coding RNA MALAT1 activates the NRF2 transcription factor, enhancing the expression of antioxidant genes such as HO1, NQO1, and GCLC, which helps protect cells from oxidative stress-induced damage [167]

Tau associated peripheral and central neurodegeneration: Identification of an early imaging marker for tauopathy