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Metformin promotes mitophagy in mononuclear cells: a potential in vitro model for unraveling metformins mechanism of action

Calculation of an OMIT map

Finally, when mutating the three boxes (Cla+Arr+W), the binding affinity reduction was the strongest for Ent1 ( K D App 3450 M, almost 25x) while the K D App for Ent2 is 1040 M