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Regulators such as the FDA and TGA warn that there is not enough evidence to declare BPC157 safe or effective for defined medical conditions

Similarly, authors [3] of the first double-blind, randomized, placebo-controlled clinical trial of oral glutathione supplementation performed in healthy adult humans concluded that despite the biochemical plausibility, optimal dose, recommended timing of administration and appropriate choice of outcome measures, no significant changes were observed in oxidative stress biomarkers or erythrocyte glutathione concentrations following 4 weeks of oral (2 x 500mg daily) glutathione supplementation

These results emphasize the suitability of RGMa, instead of neogenin, as a therapeutic target for treating diabetes-associated cognitive decline

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