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The hyper activation of HPA axis stimulate overproduction of cortisol, while down regulation of HPG axis results in the production of subnormal levels of gonadotropic hormones

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This can cause fatigue, pale skin, and shortness of breath, as the body struggles to transport oxygen efficiently

Drugs targeting the gut-liver crosstalk Microbiota transplantation Fecal transplantation has emerged as a treatment option for NAFLD, as the gut microbiota differ between NAFLD patients and healthy people