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From a translational perspective, integration of PWE or related polyphenol-rich formulations into preventive or early-intervention strategies, alone or in combination with standard pharmacotherapies, warrants investigation to define efficacy, safety, optimal dosing and patient subsets most likely to benefit

In vivo, EGCGZn suppositories effectively alleviated radiation-induced intestinal injury, as reflected by improvements in intestinal morphology, inflammatory responses, DNA damage, and mucosal barrier integrity

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