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Long-Term Safety Considerations While 24-week human trials provide reassurance about short-to-medium term safety, very long-term data (multi-year continuous use) is limited

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This is particularly important if you are part of any of the groups considered to be at high risk of B12 deficiency, including alcoholics, smokers, those on diabetes drugs, adults over 65, those with gastrointestinal disorders and those who have had surgery relating to the digestive tract