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Schoon: nothing to disclose Poster Session II - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.06 - IMAGING - Hyperacute P664 - ESOC25-913 THE IMPACT OF CT PERFUSION ON ACCURACY AND SPEED OF MEDIUM / DISTAL VESSEL OCCLUSION DETECTION ACROSS DIVERSE MEDICAL EXPERTISE - A MULTI-READER DIAGNOSTIC ACCURACY STUDY Victor Schulze-Zachau 1 , Anh Nguyen 1 , Tim Sinnecker 2 , Matthias Mutke 1 , Nadja Krug 1 , Leander Clnin 3 , Johannes Kaesmacher 3 , Marios Psychogios 1 1 Diagnostic and Interventional Neuroradiology Department, Basel University Hospital, Basel, Switzerland, 2 Neurology Clinic, Basel University Hospital, Basel, Switzerland, 3 Neuroradiology Clinic, Inselspital Bern / Bern University Hospital, Bern, Switzerland Background and Aims: Medium / distal vessel occlusions (MDVOs) are frequent and often considered for endovascular therapy

Instead the range of laboratory reference values are shifted downward to reflect those in human subjects as they advance in age

Also, a strong capacity of ADCC is able to overcome these inhibitory signals

We selected ZH-161 and ZH-305 models with constitutive c-MET activation and included a c-MET-negative model, T-269, as a reference (Fig

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