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We therefore suggest that the intracellular steady-state oxidation of roGFP2 predominantly reflects the ability of the fused glutaredoxin to form a productive ternary complex with GSH and roGFP2(S 2 )

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In the first clinical study on BBB disruption using LITT, the permeability of the BBB increased after hyperthermia, with higher permeability peaking a few days to a few weeks after the procedure 119