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However, the few reports of CBD activity alone against GBM demonstrate a good response, with the concentration required to inhibit cell growth by 50% (GI 50 ) ranging from 10.67 0.58 M against GL216 [33] and 12.75 9.7 M against U87MG [34,35,36,37,38] to 21.6 3.5 M against U373MG [36]

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A Randomized, multicenter, open-label, blinded end point, phase 2, feasibility, efficacy, and safety trial of preoperative microvascular protection in patients undergoing major abdominal surgery

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For time course assay of liposome leakage, 1 M MeCbl or DMF was pretreated with 0.4 M His-sumo-GSDME, then incubated with 0.2 M active-caspase-3 for another 2 h