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Some of the listed COB-IDs are restricted from modification including the NMT (0x00) and SDOs (0x581 to 0x67F) - see also the table of restricted COB-IDs

3 Protect: Finish with Invisible Sun Protection Gel SPF 60 to prevent UV damage

The study was approved by the University of Louisville Institutional Review Board (IRB number: 14.0614, S1 Protocol)

Supplementary Table 4: sgRNA sequences for pooled validation and CROP-seq libraries These tables show the protospacer sequences for sgRNAs in the pooled validation and CROP- seq libraries