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This method comprehensively covered the entire spectrum of carnitine and acylcarnitines, ranging from short- to long-chain, without requiring derivatization or the addition of ion-pairing reagents

Alteration of several metabolic enzymes and pathways that affect KG abundance and KGDD activity have been reported in cancer, such as mutations of the genes encoding isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2), changes in glutaminolysis that deplete KG, and alterations in fumarate hydratase and succinate dehydrogenase that inhibit KGDD activity 11

Conclusions: Higher levels of C3DC, C10:1, and C10:2 were protective factors for breast cancer, whereas increased C4 levels were a risk factor for the disease

Stage of change and motivation to healthier lifestyle in non-alcoholic fatty liver disease

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