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doi: 10.1371/journal.pone.0001205 263

Excitotoxicity was originally studied in animals but in order to understand the mechanisms underlying this process, cell culture models were developed (for review Choi, 1988)

51 N-acetylcysteine inhibits NF-B activation by suppressing TNF-induced IB kinases, followed by impediment of proteasome-dependent degradation

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This pathway is primarily transcriptionally regulated (Yura, Nagai and Mori, 1993), so RT-qPCR was performed on a subset of heat shock genes representing two major groups of heat shock genes in L