glutathione l-glutanate bacteria The System: A Journey from Cyanobacteria to Higher Eukaryotes Glutamine metabolism and its effects

NADPH-FSP1-CoQ10 pathway In the study of the ferroptosis-resistant cell line MCF7, the researchers screened the complementary gene for GPX4 deletion and found the apoptosis-inducing factor mitochondrial 2 (AIFM2) gene, which was initially found to induce apoptosis, and the researchers named it ferroptosis suppressor protein 1 (FSP1) [22]

Data availability Data are available from the corresponding author upon reasonable request

10.1038/s41569-022-00735-4 40 FengX.DuM.LiS.ZhangY.DingJ.WangJ.et al (2023)

Defective cholesterol clearance limits remyelination in the aged central nervous system

During the antigen recognition process, ROS are generated which function as second messengers to activate inflammatory signaling networks like MAPK and NF-B, and GSH buffering maintains the conditions to support those pathways (Schieber and Chandel, 2014)